Two weeks after romping 70-48 in Tuscaloosa, the Wildcats (21-0, 8-0 Southeastern Conference) made 24 of 41 from the field to surpass their previous best of 58 percent against Boston University in November.
Kentucky also committed just five turnovers while forcing Alabama (13-8, 3-5) into 13 mistakes that resulted in 20 points.
Towns scored 12 points in the first half to put Kentucky ahead. Willie Cauley-Stein snapped out of a mini-slump with 12 points and four rebounds, Devin Booker added 11 points with three 3-pointers and Aaron Harrison had 10.
Shannon Hale's 13 points led the Crimson Tide, who shot 46 percent but fell behind as Towns made all four shots to get Kentucky started.
