The Atlantic Coast Conference newcomers are looking forward to proving they can play with the best in the league. But to pull off the upset will be challenge for the Cardinals.
Both teams are coming off a bye week and the second-ranked Seminoles are determined to remain unbeaten.
It will be the first meeting between FSU (7-0, 4-0 ACC, No. 2 CFP) and Louisville (6-2, 4-2, No. 25 CFP) since Sept. 26, 2002, and the Cardinals beat a fourth-ranked Seminoles squad 26-20 in overtime. Another upset would create a seismic shift of the championship landscape.
The defending national champions haven't been as dominant this year, but have a nation-best 23 game winning streak.