The Wildcats (17-6, 7-3 Southeastern Conference) ended a rare two-game losing streak while improving to 15-0 at home.
Murray also made a career-best eight of Kentucky's season-high 12 3-pointers. He set the tone for the blowout with 20 points in the first half.
Tyler Ulis had 18 points for the Wildcats, and Derek Willis finished with 12.
Kentucky blew a 21-point lead in an 84-77 loss at Tennessee in its last outing. It got off to another fast start against the Gators, but closed it out with ease this time around.
Dorian Finney-Smith led the Gators (15-8, 6-4) with 24 points. John Egbuno had 12 points.
