Rozier closed Louisville's scoring with five free throws down the stretch along with three 3-pointers to quash the Hilltoppers' hopes of seizing momentum following Harrell's exit with 38.7 seconds remaining in the first half. The preseason first-team All-American was assessed a flagrant-2 foul for throwing an elbow following a shoving match after a loose ball scramble.
Chris Jones added 10 points for Louisville (10-0), which made 5 of 10 from long range in the second half to keep a safe cushion against WKU (5-5).
T.J. Price scored 24 points and D.J. Clayton 14 for the Hilltoppers, who got within 73-67 with 39 seconds left before Rozier added three free throws to seal the game.