Caldwell (7-0, 1-0) is undefeated and leads the state in scoring at 60 points per game. Murray's (5-2, 2-0) only losses this season are to Mayfield and Graves County.
Last year, Caldwell won the regular season game 42-13, but Murray got revenge in the playoffs. Caldwell quarterback Elijah Sindelar was picked off three times and Murray prevailed 27-14 in the regional championship game.
Kickoff is set for 7pm at Ty Holland Stadium.
Other local games tonight:
Madisonville-North Hopkins (4-3, 2-0) at Calloway County (1-6, 1-1) 7pm
Graves County (4-3, 2-0) at Christian County (3-4, 2-1) 7pm
Ballard Memorial (6-2, 0-2) at Crittenden County (3-4, 0-1) 7pm
Henderson County (3-4, 1-0) at Marshall County (2-5, 0-1) 7pm
Fulton County (1-5, 1-1) at Mayfield (6-1, 1-0) 7pm
Daviess County (2-5, 0-1) at McCracken County (6-1, 1-0) 7pm
Trigg County (4-3, 1-0) at Paducah Tilghman (3-5, 1-0) 7pm