The Dodgers were looking to build on a 3 1/2-game lead over San Francisco in the NL West after clinching a playoff spot for the fifth time in nine years on Friday.
Instead Los Angeles blew a five-run lead and wasted a pair of homers and five RBIs by Adrian Gonzalez.
The Dodgers were up 7-2 in the seventh, but the bullpen couldn't hold the lead.
J.P. Howell gave up an RBI single to Anthony Rizzo and a three-run homer to Arismendy Alcantara, making it a one-run game.
Wilson (2-4) came on in the eighth and things just got worse from there.