Lyons, who was promoted from Triple-A Memphis after Garcia went on the disabled list, allowed one run and four hits. The 25-year-old left-hander was a ninth-round draft pick in 2010 out of Oklahoma State.
The Cardinals announced before that game that Garcia will have season-ending shoulder surgery this week. The lefty went 5-2 with a 3.58 ERA in nine starts this year, helping St. Louis bolt to the majors' best record at 30-16.