Chicago wasted a 4-2 lead in the eighth after failing to protect a 5-2 seventh-inning advantage on Friday and a 7-1 ninth-inning margin on Saturday. White Sox relievers allowed 17 runs, 15 hits and eight walks over 6 1/3 innings in the three-game series, and Chicago has lost 14 of its last 18 games.
Seeking to become the major leagues' first 10-game winner, Chris Sale left with a 4-2 lead after seven innings.
