Lester will be fully rested when he pitches Tuesday night at Cleveland. Corey Kluber will start for the Indians.
The 32-year-old lefty is 2-0 in three starts during this postseason, with wins over the Giants and Dodgers in the NL playoffs. He was 19-5 during the regular season.
Lester is 3-0 in three starts in the World Series with a sparkling 0.43 ERA. He helped the Boston Red Sox win championships in 2007 and 2013.
Cubs manager Joe Maddon says Lester is "really, really in the moment" right now.
