The 37-year-old Streelman had 10 birdies, including eight in an 11-hole stretch, at Jackson Country Club.
Trey Mullinax, Seamus Power and Carl Pettersson were tied for second at 65. Seven others, including Lucas Glover and Camilo Villegas, were three back of the lead.
Streelman is a two-time PGA Tour winner, with his last victory in 2014 at the Travelers Championship. He missed the cut two weeks ago in the season-opening Safeway Open.
Defending champion Peter Malnati shot a 71.