The U.S. Food and Drug Administration, in coordination with the U.S. Department of Justice, has announced that the U.S. Marshals Service seized approximately 73,000 units of 7-hydroxymitragynine (7-OH) products—valued at roughly $1 million—from three firms in Missouri.

The seizure focused on foods and dietary supplement products—including liquid shots and tablets—containing concentrated 7-OH as an added ingredient. Concentrated 7-OH is increasingly recognized as having potential for abuse because of its ability to bind to opioid receptors. It cannot be lawfully added to dietary supplements or conventional foods. These products are considered adulterated because 7-OH does not meet applicable safety standards. Also, the FDA has not approved 7-OH for medical use.

“This enforcement action is a strong step to protect Americans from the dangers of concentrated 7-OH products, which are potent opioids,” said FDA Commissioner Marty Makary. “We must be proactive and vigilant to address emerging threats to our communities and our kids.”

Last month, Gov. Andy Beshear announced his administration is taking action to prevent the sale and distribution of 7-OH, by moving to classify it as a Schedule I narcotic. This designation makes it illegal to sell, possess or distribute any isolated or concentrated forms of 7-OH, as well as kratom in the state.

“We have marked three straight years of declines in overdose deaths in Kentucky and that is progress we’re committed to building on as we work to protect more lives in the fight against addiction,” Beshear said. “Deadly and addictive drugs like 7-OH have no place in our communities, and this step will help us get these drugs off the streets and provide us more tools to keep Kentuckians safe.”

The Cabinet for Health and Family Services is in the process of updating regulations to classify isolated and concentrated forms of 7-OH as Schedule I substances – the same category as heroin, LSD and fentanyl analogs.

Once final, this action will allow law enforcement and regulatory agencies to immediately begin removing these unsafe products from retail shelves statewide. That could come before the General Assembly’s Administrative Regulation Review Subcommittee next month.

“When kratom is altered to create synthetic opioids, it becomes a threat to the public’s health,” said Cabinet for Health and Family Services Secretary Dr. Steven Stack. “It puts people at risk and undermines the strides Kentucky has made in reducing the scourge of addiction.”


“When kratom is altered to create synthetic opioids, it becomes a threat to the public’s health,” said Cabinet for Health and Family Services Secretary Dr. Steven Stack. “It puts people at risk and undermines the strides Kentucky has made in reducing the scourge of addiction.”